The Binding Sites of Inhibitory Monoclonal Antibodies on Acetylcholinesterase
نویسندگان
چکیده
منابع مشابه
Immunochemical characterization of anti-acetylcholinesterase inhibitory monoclonal antibodies.
Monoclonal antibodies (mAbs) were prepared against native or DFP-inhibited Torpedo californica acetylcholinesterase and native or DFP-, MEPQ-, and soman-inhibited fetal bovine serum acetylcholinesterase. The cross reactivity of these antibodies with acetylcholinesterases from various species and their ability to inhibit catalytic activity were determined. Eight antibodies were found to inhibit ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1999
ISSN: 0021-9258
DOI: 10.1074/jbc.274.39.27740